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During the European School of Haematology (ESH)'s 2nd How to Diagnose & Treat Lymphoma conference, the Lymphoma Hub spoke to Andrew Davies, University of Southampton, Southampton, UK. We asked, When will we be seeing changes in the frontline treatment of diffuse large B-cell lymphoma (DLBCL)?
When will we be seeing changes in the frontline treatment of DLBCL?
Andrew Davies starts by describing the changes in treatment selection that has already started to occur for patients with standard risk disease. He then discusses the situation for patients with high-risk DLBCL, which is yet to undergo such a shift. The different approaches that have been tested are listed, but it is acknowledged that R-CHOP protocols remain the standard of care for this group. The impact of molecular profiling and patient stratification are examined.